Antibody drug conjugates (ADCs) for cancer treatments refer to a relatively new type of cancer immunotherapy that applies monoclonal antibodies to locate specific malignant cells and meanwhile relies on chemotherapeutic drugs to destroy them. In an ADC, the antibody and the drug ...Learn More

Q1: Who firstly presented the concept of antibody drug conjugate?

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The pCas/pTargetF system is one of the most popular genomic editing systems in E. coli. According to data from MolecularCloud, Addgene and our laboratory, there were 723 and 615 usage records in total for pCas and pTargetF respectively. However, few users pointed out that this ...Learn More

Despite the difficulties that certain countries are experiencing during the implementation of an effective vaccination strategy, the global SARS-CoV-2 pandemic has led to a collective effort for the generation of effective and safety vaccines in a very short time. At present there ...Learn More

Introduction of the prime editing vectors developed in Chen Lab Recently, a novel, universal, and precise genome-editing technology named prime editing was developed (Anzalone et al. Nature. 2019, 576: 149–57). We generated a set of pGreen3 binary vectors for prime editing in ...Learn More

Nanotechnology has shown an important potential in the immunotherapeutic field, as the modulation of a variety of immune processes can be achieved both in vitro and in vivo. Nanotechnology can be used to promote the immune activation or to induce tolerance depending on the ...Learn More

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