Trent Woodruff
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Neuroinflammation 0 Innate Immune System 0 C5a Receptor 0 Neurodegenerative Diseases 0

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Lo MW, Kemper C, Woodruff TM. COVID-19: Complement, Coagulation, and Collateral Damage [published online ahead of print, 2020 Jul 22]. J Immunol. 2020;ji2000644. doi:10.4049/jimmunol.2000644
Li XX, Lee JD, Massey NL, et al. Pharmacological characterisation of small molecule C5aR1 inhibitors in human cells reveals biased activities for signalling and function [published online ahead of print, 2020 Jul 17]. Biochem Pharmacol. 2020;180:114156. doi:10.1016/j.bcp.2020.114156
Lee JD, McDonald TS, Fung JNT, Woodruff TM. Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1G93AMouse Model of Amyotrophic Lateral Sclerosis [published online ahead of print, 2020 Jul 16]. Mol Neurobiol. 2020;10.1007/s12035-020-02019-9. doi:10.1007/s12035-020-02019-9
Kumar V, Lee JD, Coulson EJ, Woodruff TM. A validated quantitative method for the assessment of neuroprotective barrier impairment in neurodegenerative disease models [published online ahead of print, 2020 Jul 6]. J Neurochem. 2020;10.1111/jnc.15119. doi:10.1111/jnc.15119
Li XX, Clark RJ, Woodruff TM. C5aR2 Activation Broadly Modulates the Signaling and Function of Primary Human Macrophages. J Immunol. 2020;205(4):1102-1112. doi:10.4049/jimmunol.2000407
Gordon R, Albornoz EA, Christie DC, et al. Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice. Sci Transl Med. 2018;10(465):eaah4066. doi:10.1126/scitranslmed.aah4066

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