Matthew S. Gentry

Dr. Gentry received his B.S. from the University of Evansville in 1996. He then studied yeast cell cycle regulation via protein phosphatase 2A at Syracuse University in Dr. Richard Hallberg’s lab, receiving his Ph.D. in 2003. He was a postdoctoral fellow at UC-San Diego with Dr. Jack Dixon where he discovered glycogen and starch phosphatases and how they are integral for both human and plant energy metabolism. He began his independent career in 2008 and he is currently a Professor in the College of Medicine at the University of Kentucky where he oversees projects on both Lafora disease and biofuels research. The lab focuses on the regulation of specific phosphatases and E3 ubiquitin ligases in both human glycogen and plant starch metabolism utilizing in vitro biochemical and structural techniques; in situ cell culture models; and in vivo mouse, algal and plant models. Dr. Gentry has been continuously funded by NINDS since 2006, he is an NIH K99/R00 Pathway to Independence Award recipient, he received the NIH Young Investigator IDeA Maciag Award, he is an NSF CAREER awardee, and PI of both a NINDS R01 and P01. He is a Journal of Biological Chemistry Editorial Board member, he is on the Executive Committee of the ASBMB Public Action Advocacy Committee (PAAC), and he is a member multiple study sections.

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Gentry Lab, College of Medicine, University of Kentucky

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  1. Gentry MS, Brewer MK, Vander kooi CW. Structural biology of glucan phosphatases from humans to plants. Curr Opin Struct Biol. 2016;40:62-69.

  2. Emanuelle S, Brewer MK, Meekins DA, Gentry MS. Unique carbohydrate binding platforms employed by the glucan phosphatases. Cell Mol Life Sci. 2016;73(14):2765-2778.

  3. Meekins DA, Vander kooi CW, Gentry MS. Structural mechanisms of plant glucan phosphatases in starch metabolism. FEBS J. 2016;283(13):2427-47.


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