Christopher Chen

Dr. Chen received his A.B. in Biochemistry from Harvard, M.S. in Mechanical Engineering from MIT, and Ph.D. in Medical Engineering and Medical Physics from the Harvard-MIT. Health Sciences and Technology Program. He earned his M.D. from the Harvard Medical School. Dr. Chen was previously Assistant Professor in Biomedical Engineering and in Oncology at Johns Hopkins University, the Skirkanich Professor of Innovation and founding director of the Center for Engineering Cells and Regeneration at the University of Pennsylvania. He is currently a professor of Biomedical Engineering and director of the Tissue Microfabrication Laboratory at Boston University. The goal of Dr. Chen’s research is to identify the underlying mechanisms by which cells interact with materials and each other to build tissues, and to apply this knowledge in the biology of stem cells, tissue vascularization, connective tissues, and cancer.

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Boston University

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Microfabrication and nanotechnology 0 Cell and tissue engineering 0 Regenerative medicine 0

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  1. Chen, Christopher S., et al. "Geometric control of cell life and death." Science 276.5317 (1997): 1425-1428.

  2. McBeath, Rowena, et al. "Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment." Developmental cell 6.4 (2004): 483-495.

  3. Tan, John L., et al. "Cells lying on a bed of microneedles: an approach to isolate mechanical force." Proceedings of the National Academy of Sciences 100.4 (2003): 1484-1489.

  4. Maniotis, Andrew J., Christopher S. Chen, and Donald E. Ingber. "Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure." Proceedings of the National Academy of Sciences 94.3 (1997): 849-854.

  5. Guilak, Farshid, et al. "Control of stem cell fate by physical interactions with the extracellular matrix." Cell stem cell 5.1 (2009): 17-26.

  6. Miller, Jordan S., et al. "Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues." Nature materials 11.9 (2012): 768-774.


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