Ashutosh Chilkoti

Ashutosh Chilkoti is the Alan L. Kaganov Professor of Biomedical Engineering and Chair of the Department of Biomedical Engineering at Duke University. His research in biomolecular engineering and biointerface science focuses on the development of new molecular tools and technologies that borrow from molecular biology, protein engineering, polymer chemistry and surface science that they then exploit for the development of applications that span the range from bioseparations, plasmonic biosensors, low-cost clinical diagnostics, and drug delivery.

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Duke University

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Biomolecular Engineering 0 Biomolecular Materials 0 Protein-Polymer Conjugates 0 Plasmonic Biosensors 0

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  1. J. Wang, Min, J. , Eghtesadi, S. Ali, Kane, R. S. , and Chilkoti, A. , “A Quantitative Study of the Interaction of Multivalent Ligand-Modified Nanoparticles with Breast Cancer Cells with Tunable Receptor Density”, ACS Nano, 2020.

  2. S. Saha, Banskota, S. , Roberts, S. , Kirmani, N. , and Chilkoti, A. , “Engineering the Architecture of Elastin‐Like Polypeptides: From Unimers to Hierarchical Self‐Assembly”, Advanced Therapeutics, vol. 3, no. 3, 2020.

  3. S. Roberts, Miao, V. , Costa, S. , Simon, J. , Kelly, G. , Shah, T. , Zauscher, S. , and Chilkoti, A. , “Complex microparticle architectures from stimuli-responsive intrinsically disordered proteins”, Nature Communications, vol. 11, no. 1342, 2020.

  4. F. Garcia Quiroz, Li, N. K. , Roberts, S. , Weber, P. , Dzuricky, M. , Weitzhandler, I. , Yingling, Y. G. , and Chilkoti, A. , “Intrinsically disordered proteins access a range of hysteretic phase separation behaviors”, Science Advances, vol. 5173193363355141541046164516151063419184550218545550, no. 10, p. eaax5177, 2019.

  5. J. Wang, Saha, S. , Schaal, J. L. , Yousefpour, P. , Li, X. , and Chilkoti, A. , “Heuristics for the Optimal Presentation of Bioactive Peptides on Polypeptide Micelles”, Nano Letters, vol. 19, no. 11, pp. 7977 - 7987, 2019.

  6. J. R. Simon, Eghtesadi, S. Ali, Dzuricky, M. , You, L. , and Chilkoti, A. , “Engineered Ribonucleoprotein Granules Inhibit Translation in Protocells”, Molecular Cell, 2019.


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