Alfonso Jaramillo

Prof. Alfonso Jaramillor received a PhD in Particle Physics in 1999, before his postdoctoral appointments with Prof. Wodak (ULB Brussels, 1999-2002) and Prof. Karplus (ULP France and Harvard USA, 2002-2003). In 2003, Prof. Jaramillor as Assistant Professor at the Ecole Polytechnique in France, where he began developing computational design methods for Biology. Then, as senior researcher at CNRS-Genopole (2009), he developed and utilized automated microscopy and microfluidics chips for single-cell validations. Prof. Jaramillor moved to the University of Warwick in 2013, where he holds the Chair of Synthetic Biology as a Full Professor. Prof. Alfonso’s lab focuses on the development of technologies for synthetic biology based on evolution; they are working on synthetic bacteriophages and the engineering of novel riboswitches for de novo bimolecular and metabolic engineering, through methodologies developed in the lab. Prof. Alfonso intends to showcase the therapeutic availability of synthetic bacteriophages by engineering a phage therapy against antibiotic-resistant bacteria, hence promoting more efforts from synthetic biology towards its therapeutic potential.

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The University of Warwick

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Synthetic Biology 0 Synthetic Bacteriophage 0 Engineered Riboswitches 0 Automated Genetic Engineering 0 Synthetic regulatory circuits 0

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  1. Grigonyte, Aurelija, Harrison, Christian, Macdonald, Paul R., Montero-Blay, Ariadna, Tridgett, Matthew, Duncan, John, Sagona, Antonia, Constantinidou, Chrystala, Jaramillo, Alfonso, Millard, Andrew D., 2020. Comparison of CRISPR and marker-based methods for the engineering of Phage T7. Viruses, 12 (2)

  2. Broedel, A., Rodrigues, R., Jaramillo, Alfonso, Isalan, M., 2020. Accelerated evolution of a minimal 63-amino acid dual transcription factor. Science Advances, 6 (24)

  3. Galizi, Roberto, Jaramillo, Alfonso, 2019. Engineering CRISPR guide RNA riboswitches for in vivo applications. Current Opinion in Biotechnology, 55, pp. 103-113

  4. Howarth, Mark, Jaramillo, Alfonso, 2018. Editorial overview : nanobiotechnology : baby steps and giant strides towards molecular mastery. Current Opinion in Biotechnology, 51, pp. iv-vi

  5. Ferreira, Eunice A., Pacheco, Catarina C., Pinto, Filipe, Pereira, José, Lamosa, Pedro, Oliveira, Paulo, Kirov, Boris, Jaramillo, Alfonso, Tamagnini, Paula, 2018. Expanding the toolbox for Synechocystis sp. PCC 6803 : validation of replicative vectors and characterization of a novel set of promoters. Synthetic Biology, 3 (1)


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