What is CAR-T Cell Therapy?

"Everyone is a writer" program aims to promote the sharing of knowledge and learning together. There are some answers about the CAR-T Cell Therapy from this campaign.

Q: What is CAR-T Cell Therapy?

A: Lauren Escobedo: Cancer has affected millions of people all across the world. There are many methods to reduce or eliminate the cancerous disease that is invading it’s host. One form of treatment is called CAR-T cell therapy which highlights the immunotherapy aspect. The treatment main focus is conducting laboratory work in which the patient’s T-cells are manipulated and reinserted into the patient. Learn More

Manini Penikalapati: In recent years, a new treatment for cancer has been adopted: immunotherapy. Immunotherapy is based on strengthening the patient’s own immune system to attack tumors. A particularly successful and novel type of immunotherapy is CAR-T cell therapy. CAR-T therapy involves separating out the T cells from a patient’s blood and engineering them to produce chimeric antigen receptors (CARs). Learn More

Lily Honsman: Chimeric antigen receptor T cells (also known as CAR T cells) are T cells that have been genetically engineered to produce an artificial T-cell receptor for use in immunotherapy. CAR-T cell therapy uses T cells engineered with CARs for cancer therapy. The CAR-T cells are able to bind to an antigen on the cancer cells and kill them. Learn More

Zoe Fang: CAR T-cell therapy is a type of cancer therapy that uses a patient’s own modified white blood cells to kill cancer cells. T cells are changed in the laboratory. The gene for a special receptor called a chimeric antigen receptor (CAR) will insert into the T cells. Then millions of the CAR T cells are grown in the laboratory and then given to the patient by infusion. The CAR T cells are able to bind to an antigen on the cancer cells and kill them. Learn More

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