Gene therapy involves the transfer of genetic material and the uptake of the gene into the appropriate cells of the body. Cell therapy involves the transfer of cells with the relevant function into the patient.
This article is reprinted from Lapipette. Link: https://lapipette.com/CAR-TCAR-T, a revolutionary cell therapy for cancer has been recently approved by the FDA. But what is it about?The idea of immunotherapy or using our own immune system against cancer has been around for more ...Learn More
For most of the past four decades, it was considered that there were only two T cell lineages, αβ and γδ T cells, characterized by their cell surface expressed αβ and γδ TCRs, respectively. However, recently, biologists have found a previously unknown lineage, called γµ ...Learn More
Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition https://www.cell.com/cell/fulltext/S0092-8674(21)00002-7?rss=yes Checkpoint inhibitors (CPIs) augment adaptive immunity. Systematic pan-tumor analyses may reveal the relative ...Learn More
"Uncharted Territory: Top Challenges Facing Gene Therapy Development". Scientists from three different institutions—St. Jude Children’s Research Hospital, SCIEX, and Sanofi— share their perspectives on the future of gene therapy. Here are more details of this ...Learn More
CAR T-cell therapy, like all forms of cancer immunotherapy, seeks to sharpen and strengthen the immune system’s inherent cancer-fighting powers. It involves treating patients with modified versions of their own immune system T cells – white blood cells that help protect the ...Learn More