Gene and cell therapy (GCT) is one of the fastest growing segments in the biopharmaceutical industry. Starting first with the approval and use for autologous CD54+ antigen presenting cells by the Food and Drug Administration (FDA), followed by several other allogeneic ...Learn More

Immuno-oncology, known as Cancer immunotherapy, is a type of biotherapy that uses components from live organisms to treat cancer. It is also known as biologic therapy or biological response modifier (BRM) therapy. It's a cancer treatment that harnesses the body's immune system's ...Learn More

Dr. Zuris discussed the rationale and approach for generating a new AsCas12a variant or AsCas12 ULTRA, how the newly developed variant compares in activity and specificity against other nucleases, and its application to T and NK cell gene editing.

When it comes to fighting cancer, the most important battle happens in the immune system – and leading this fight are T cells, the soldiers of the immune system. CAR T cell therapy is one way City of Hope scientists are empowering a patient’s own immune system to fight cancer. ...Learn More

CAR-T cells are part of the new arsenal of revolutionary immunotherapeutics, which have radically changed cancer treatment. These genetically engineered T cells are modified to express novel “Chimeric Antigen Receptors” or CARs, endowing them with unique tumor-killing ...Learn More