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I’m Xueli Zhang, a Principal Investigator of the Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences. My research focuses on constructing microbial cell factories for production of bulk chemicals and plant-derived natural products through metabolic engineering and synthetic biology. Research interests include: (1) Identification of new enzymes for natural products synthesis using metabolic engineering platforms, followed by enzyme optimization. (2) Design and construction of synthetic pathways, followed by pathway optimization through coordinated gene expression, cofactor engineering and metabolic evolution. (3) Optimization of cell physiology through adaptive evolution, followed by characterization of their genetic mechanisms. (4) Development of new genome editing methods.

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