siRNA, with a molecular weight of about 13 kDa, recruits the RNA-induced silencing complex (RISC) to mRNA through base pairing, thereby inhibiting protein translation (Fig. 1). The mRNA is targeted for cleavage through the catalysis of the RISC protein Ago2, a member of the ...Learn More

Proteins are the workhorses of life, involved in an astonishing array of biological processes. To truly understand how they function, we must delve deep into their structural intricacies. One of the most powerful techniques for revealing the three-dimensional architecture of ...Learn More

Understanding protein-protein interactions is pivotal in unraveling complex biological processes. A comprehensive understanding of these interactions sheds light on various cellular functions and enables the development of targeted therapeutics. In this technical support article, ...Learn More

In the realm of molecular biology and protein biochemistry, scientists employ a variety of techniques to delve into the intricate world of proteins. One such fundamental method is SDS-PAGE, which stands for Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis. The core ...Learn More

For scientists venturing into the intricate world of protein research, the quest for functional proteins is a defining challenge. These proteins, the workhorses of life, hold the secrets of vital biological processes. Unfortunately, their complex structures remain beyond the reach ...Learn More