Elizabeth Gabriela Macedo Flores
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Biomedical Science 0 Biological Engineering 0 Genome Editing 1 Genomics 0
You may have heard of genomes being sequenced. For instance, the human genome was completed in 2003, after a many-year, international effort. But what does it mean to sequence a genome, or even a small fragment of DNA?DNA sequencing is the process of determining the sequence of ...Learn More
Step 1: Replication Fork FormationBefore DNA can be replicated, the double stranded molecule must be “unzipped” into two single strands. DNA has four bases called adenine (A), thymine (T), cytosine (C) and guanine (G) that form pairs between the two strands. Adenine only pairs ...Learn More
There are a wide variety of medical applications for DNA sequencing. These techniques can be used to test one gene or several genes to help diagnose medical conditions. Some examples include:Targeted sequencing—sequencing of select variants or areas within a gene's exons or full ...Learn More
Massive parallel DNA sequencing (synonyms are: DNA deep sequencing | DNA high-throughput sequencing | DNA-seq) includes Whole Genome Sequencing (WGS), Whole Exome Sequencing (WES or WXS) and targeted sequencing. WGS implies sequencing of the entire DNA genome, while WES focuses on ...Learn More
DNA sequencing is a laboratory method used to determine the order of the bases within the DNA. Differences in the sequence of these 3 billion base pairs in the human genome lead to each person's unique genetic makeup. In medicine, DNA sequencing is used for a range of purposes, ...Learn More
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