Damian Holsinger

Dr Damian Holsinger received his Doctorate in Molecular Neuroscience from The University of Melbourne, Australia and is currently Head of the Laboratory of Molecular Neuroscience and Dementia at The University of Sydney. He received his undergraduate training at The University of Toronto and an MSc degree from McMaster University in the fields of neurophysiology and molecular biology. Dr Holsinger’s laboratory focuses on understanding the molecular underpinnings of neurodegenerative diseases, in particular Alzheimer’s and identifying therapeutic avenues for these devastating diseases via repurposing strategies. His research interests have also recently embodied the field of Biomedical Engineering where current research in the laboratory is investigating the modification of biomolecular scaffolds for therapeutic purposes.

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Laboratory of Molecular Neuroscience and Dementia

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Molecular neuroscience 0 glial cell biology 0 healthy ageing 0 translation research 0

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Hello everyone! I have successfully joined Cloud Scientist program! I’m Damian Holsinger, Head of the Laboratory of Molecular Neuroscience and Dementia at The University of Sydney. I received my doctorate in Molecular Neuroscience from The University of Melbourne, Australia. ...Learn More

  1. 1. Gaukås NH, Huynh Q¬S, Pratap AA, Einarsrud M¬A, Grande T, Holsinger RMD* and Glaum J*. (2020) In vitro biocompatibility of piezoelectric K0.5Na0.5NbO3 thin films on platinized silicon substrates. ACS Applied BioMaterials (accepted October 28, 2020)

  2. 2. Kosaraju J, Holsinger RMD, Guo L, Tam KY. (2017) Linagliptin, a Dipeptidyl Peptidase¬4 Inhibitor, Mitigates Cognitive Deficits and Pathology in the 3xTg¬AD Mouse Model of Alzheimer's Disease. Molecular Neurobiology, 54(8): 6074–6084.

  3. 3. Rollo JL, Banihashemi N, Vafaee F, Crawford J, Kuncic Z and Holsinger RMD. (2016) Unravelling the mechanistic complexity of Alzheimer’s disease through systems biology. Alzheimer’s and Dementia, 12(6):708-18.

  4. 4. Holsinger RMD, McLean CA, Collins CJ, Masters CL and Evin G. (2004) Increased beta-secretase activity in cerebrospinal fluid of Alzheimer’s disease subjects. Annals of Neurology, 55(6):898-899.

  5. 5. Holsinger RMD, McLean CA, Beyreuther K, Masters CL and Evin G. (2002) Increased expression of the amyloid precursor beta-secretase in Alzheimer’s Disease. Annals of Neurology, 51:783-786.


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