What are the major applications and advances in Synthetic biology?

Synthetic Biology offers a wide range of Applications and Advances. Here are some: 

Health - Gene editing, Personalized medicine, Tissue engineering and biologics replacing chemically-synthesized drugs. Example: Engineered Bacteria for treatment of Colon cancer. (REFERENCE: sciencemag)

Environment and Agriculture - Biosensors for detecting toxic contaminants, Bioremediation - Engineered plants and bacteria to degrade pesticides. Example: Wheat gene inserted into chestnut embryos, enabling them to make an enzyme that detoxifies the fungus. (REFERENCE: APnews)

Energy - Creates Biofuels which are less toxic and more efficient, Creates Enzymes with improved quality that works faster. Example: Synthetic biology with microfluidics to create artificial photosynthetic droplets for the production of organic chemicals and clean fuels. (REFERENCE: NCBI)

Drug development & Medicine - Synthetic biology has been used in the development of alternate production routes. Example: Artificial construction of metabolic pathway in E.coli and yeast for production of Artemisinin, an anti-malarial drug. (REFERENCE: Scitable)

Recent Advancements: 

  • Production of Engineered Bispecific antibodies.

  • CAR T-cell therapy.

  • iPSC production.


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