CRISPR (Clustered Regularly Interspaced Short
Palindromic Repeats), a revolutionary gene-editing tool which has the ability
to edit nearly any segment of DNA with more precise than any other
DNA-editing tools. This DNA editing tool is highly used in the cancer
research field in the recent years. There are a number of different cancer
types with different mutation and few genetic mutations are common between many
cancer types. These genetic mutations can either act as an oncogene or tumor
suppressor leading to uncontrolled cell growth. With the CRISPR
we can introduce specific site
mutations, silence or overexpress genes of interest, or add large sequences to change
the function of that gene and can use it to treat any cancer. Recent studies
has shown various genes and its role in cancer metastasis, with this DNA
editing tool we can precisely see the function of the gene by mutating and look
at the cancer cell behavior.
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