Induced Pluripotent Stem Cell-Derived Cerebral Organoids Provide a Platform to Screen Alzheimer's Drugs

Late onset or sporadic Alzheimer's disease accounts for over 95% of cases and is therefore the most prevalent form of the syndrome that leads to progressive neuronal atrophy and memory impairment. While sporadic disease is diagnosed on average at ~60 years of age, the first pathological changes commonly go unnoticed and may occur over 10 years before cognitive impairment is evident.

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