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Genome Editing 0 Metabolic Engineering 0
Gut microbial transformations of flavonoids, an enormous class of polyphenolic compounds abundant in plant-based diets, are closely associated with human health. However, the enzymes that initiate the gut microbial metabolism of flavones and flavonols, the two most abundant groups ...Learn More
Yang Y., L Zhang, H Huang, C Yang, S Yang, Y Gu*, W Jiang*. A flexible binding site architecture provides new insights into CcpA global regulation in Gram-positive bacteria. (2017) mBio 24:8(1).
Li J., C Wang, G Yang, Z Sun., H Guo, K Shao, Y Gu, W Jiang*, P Zhang*. Molecular mechanism of environmental D-xylose perception by a XylFII-LytS complex in bacteria. (2017) PNAS, 114(31): 8235-8241.
Li L., W Jiang*, Y Lu*. A novel two-component system, GluR-K, involved in glutamate sensing and uptake in Streptomyces coelicolor. (2017) J Bacteriol 199(18) e00097-17.
Li L., W Jiang*, Y Lu*. New strategies and approaches for engineering biosynthetic gene clusters of microbial natural products. (2017) Biotechnol Adv 35:936-949.
Li L., G Zheng, J Chen, M Ge, W Jiang*, Y Lu*. Multiplexed site-specific genome engineering for overproducing bioactive secondary metabolites in actinomycetes. (2017) Metab Eng 40: 80-92.
Meng J., R Feng, G Zheng, M Ge, Mast Y, Wohlleben W*, J Gao, W Jiang* and Y Lu*. Improvement of pristinamycin I (PI) production in Streptomyces pristinaespiralis by metabolic engineering approaches. (2017) Synth Syst Biotechnol 2:130-136.
He J., H Zhu, G Zheng, P Liu, J Wang, G Zhao, G Zhu*, W Jiang*, Y Lu*, Direct invovlement of the master nitrogen metabolism regulator in antibiotic Biosynthesis in Streptomyces. (2016) J Biol Chem. 291 (51) :26443.
Yang Y., N Lang, G Yang, S Yang, W Jiang*, Y Gu*, Improving the performance of solventogenic clostridia by reinforcing the biotin synthetic pathway. (2016) Metab Eng 35: 121-128.
Xue Q., Y Yang, J Chen, L Chen, S Yang, W Jiang*, Y Gu*, Roles of three AbrBs in regulating two-phase Clostridium acetobutylicum fermention.（2016）Appl Microbiol Biotechnol 100(21):9081-9089.
Ren C., Z Wen, Y Xu, W Jiang*, Y Gu*, Clostridia: a flexible microbial platform for the production of alcohols. (2016) Curr Opin Chem Biol 35:65-72.
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