Protein degradation is one of the most tightly regulated processes in eukaryotic cells, controlling everything from cell division and DNA repair to immune signalling and apoptosis. Central to this system are E3 ubiquitin ligases, enzymes responsible for recognising target proteins ...Learn More

The RNF2 antibody targets RNF2 (Ring Finger Protein 2), also known as RING1B or RING2, a critical E3 ubiquitin ligase and catalytic core component of the Polycomb Repressive Complex 1 (PRC1). RNF2 antibody mediates the monoubiquitination of histone H2A at lysine 119 (H2AK119ub1) ...Learn More