Cyclization of peptides has been shown to be an important tool for structure-activity studies and drug development. The ring structure of cyclic peptides can be formed through four strategies, as shown in figure 1, including “head-to-tail cyclization” ”head-to-side chain ...Learn More
Peptide nucleic acids (PNAs) are synthetic nucleic acid analogs, which were first synthesized in 1991 by Peter E. Nielsen and colleagues. As shown in figure 1, unlike DNA and RNA, the phosphate sugar backbone of PNA is replaced by repeating N-(2-aminoethyl)-glycine units. ...Learn More
The generation of custom antibodies can be accomplished by using one of two primary approaches: full length protein and short peptides, but synthetic peptide antigens are often too small to generate significant immune responses on their own.To overcome the bottleneck, synthetic ...Learn More
Fluorescent techniques are widely used in biological research, which are related to their high sensitivity, selectivity, fast response time, flexibility and experimental simplicity. Fluorescent tags or probes are ideal for many imaging and diagnostic applications, also are be used ...Learn More
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