Crotalicidin

Description:

Potent antimicrobial peptide with low cytotoxicity

Sequence:

KRFKKFFKKVKKSVKKRLKKIFKKPMVIGVTIPF-NH₂
  • General
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  • Name Crotalicidin
    Category Antimicrobial and Related Peptides
    One Letter Code KRFKKFFKKVKKSVKKRLKKIFKKPMVIGVTIPF-NH₂
    Three Letter Code {Lys}{Arg}{Phe}{Lys}{Lys}{Phe}{Phe}{Lys}{Lys}{Val}{Lys}{Lys}{Ser}{Val}{Lys}{Lys}{Arg}{Leu}{Lys}{Lys}{Ile}{Phe}{Lys}{Lys}{Pro}{Met}{Val}{Ile}{Gly}{Val}{Thr}{Ile}{Pro}{Phe}-NH₂
    Molecular Weight 4151.390
    Application Antimicrobial & Antiviral Peptides
    Falcao, Claudio Borges, et al. "Structural dissection of crotalicidin, a rattlesnake venom cathelicidin, retrieves a fragment with antimicrobial and antitumor activity." Journal of medicinal chemistry 58.21 (2015): 8553-8563.
    Falcao, C. B., et al. "Vipericidins: a novel family of cathelicidin-related peptides from the venom gland of South American pit vipers." Amino acids 46.11 (2014): 2561-2571.
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