Histone deacetylase, HDAC substrate

Description:

This novel fluorogenic substrate of HDACs was synthesized with an epsilon-acetylated lysyl moiety and an adjacent MCA moiety at the C-terminus of the peptide chain.

Sequence:

Ac-RGK(Ac)-AMC

General

References

Comments (0)

Name	Histone deacetylase, HDAC substrate
Category	Histone Sequences, DNA-Binding Peptides
One Letter Code	Ac-RGK(Ac)-AMC
Three Letter Code	Acetylation-{Arg}{Gly}{Lys(Ac)}-AMC
Molecular Weight	600.700
Application	Histone Peptides

Wegener, D. et al. Chem. Biol. 10, 61 (2003).

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