Apidaecin IB

Description:

Apidaecin IB is an insect antimicrobial peptide showing a significant sequence homology and a common mechanism of action with drosocin, but is devoid of any pore-forming activity.

Sequence:

GNNRPVYIPQPRPPHPRL
  • General
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  • Name Apidaecin IB
    Category Antimicrobial and Related Peptides
    One Letter Code GNNRPVYIPQPRPPHPRL
    Three Letter Code {Gly}{Asn}{Asn}{Arg}{Pro}{Val}{Tyr}{Ile}{Pro}{Gln}{Pro}{Arg}{Pro}{Pro}{His}{Pro}{Arg}{Leu}
    Molecular Weight 2108.400
    Application
    Casteels‐Josson, Katty, et al. "Apidaecin multipeptide precursor structure: a putative mechanism for amplification of the insect antibacterial response." The EMBO journal 12.4 (1993): 1569-1578.
    Gobbo, Marina, et al. "Antimicrobial peptides: synthesis and antibacterial activity of linear and cyclic drosocin and apidaecin 1b analogues." Journal of medicinal chemistry 45.20 (2002): 4494-4504.
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