PEP1

Description:

This peptide mimics wild-type AH (amphipathic helix) and inhibits membrane association of NS5A.

Sequence:

SGSWLRDVWDWICTVLTDFKTWLQSKLDYKD-NH2

General

References

Comments (0)

Name	PEP1
Category	Hepatitis C Virus (HCV) Related Peptides
One Letter Code	SGSWLRDVWDWICTVLTDFKTWLQSKLDYKD-NH2
Three Letter Code	{Ser}{Gly}{Ser}{Trp}{Leu}{Arg}{Asp}{Val}{Trp}{Asp}{Trp}{Ile}{Cys}{Thr}{Val}{Leu}{Thr}{Asp}{Phe}{Lys}{Thr}{Trp}{Leu}{Gln}{Ser}{Lys}{Leu}{Asp}{Tyr}{Lys}{Asp}-NH2
Molecular Weight	3805.300
Application

Elazar, Menashe, et al. "Amphipathic helix-dependent localization of NS5A mediates hepatitis C virus RNA replication." Journal of virology 77.10 (2003): 6055-6061.