HCV NS4A Protein (21-34) (JT strain)

Description:

The NS4A fragment GSVVIVGRIILSGR corresponds to the residues involved in the interaction with the NS3 protease. Unlike the NS4A fragment (22-34) CVVIVGRVVLSGK derived from the H strain, this peptide contains no cysteine residues and is hence more stable.

Sequence:

GSVVIVGRIILSGR

General

References

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Name	HCV NS4A Protein (21-34) (JT strain)
Category	Hepatitis C Virus (HCV) Related Peptides
One Letter Code	GSVVIVGRIILSGR
Three Letter Code	{Gly}{Ser}{Val}{Val}{Ile}{Val}{Gly}{Arg}{Ile}{Ile}{Leu}{Ser}{Gly}{Arg}
Molecular Weight	1425.740
Application	Virology

Steinkühler, Christian, Licia Tomei, and Raffaele De Francesco. "In vitro activity of hepatitis C virus protease NS3 purified from recombinant baculovirus-infected Sf9 cells." Journal of Biological Chemistry 271.11 (1996): 6367-6373.

Shimizu, Yasuaki, et al. "Identification of the sequence on NS4A required for enhanced cleavage of the NS5A/5B site by hepatitis C virus NS3 protease." Journal of Virology 70.1 (1996): 127-132.