(Des-His¹,Glu⁹)-Glucagon (1-29) amide (human, rat, porcine)

Description:

Glucagon antagonist.

Sequence:

SQGTFTSEYSKYLDSRRAQDFVQWLMNT-NH₂

General

References

Comments (0)

Name	(Des-His¹,Glu⁹)-Glucagon (1-29) amide (human, rat, porcine)
Category	Glucagons and Glucagon-Like Peptides (GLP-1 and GLP-2)
One Letter Code	SQGTFTSEYSKYLDSRRAQDFVQWLMNT-NH₂
Three Letter Code	{Ser}{Gln}{Gly}{Thr}{Phe}{Thr}{Ser}{Glu}{Tyr}{Ser}{Lys}{Tyr}{Leu}{Asp}{Ser}{Arg}{Arg}{Ala}{Gln}{Asp}{Phe}{Val}{Gln}{Trp}{Leu}{Met}{Asn}{Thr}-NH₂
Molecular Weight	3358.700
Application	Diabetes

Cohen, Sheila M., et al. "Direct observation (NMR) of the efficacy of glucagon receptor antagonists in murine liver expressing the human glucagon receptor." Bioorganic & medicinal chemistry 14.5 (2006): 1506-1517.

Ahn, J. M., et al. "Development of potent glucagon antagonists: structure− activity relationship study of glycine at position 4." The Journal of Peptide Research 58.2 (2001): 151-158.