Oxyntomodulin (human, mouse, rat)

Description:

Oxyntomodulin potently inhibits gastric acid secretion and pancreatic enzyme secretion

Sequence:

HSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIA

General

References

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Name	Oxyntomodulin (human, mouse, rat)
Category	Glucagons and Glucagon-Like Peptides (GLP-1 and GLP-2)
One Letter Code	HSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIA
Three Letter Code	{His}{Ser}{Gln}{Gly}{Thr}{Phe}{Thr}{Ser}{Asp}{Tyr}{Ser}{Lys}{Tyr}{Leu}{Asp}{Ser}{Arg}{Arg}{Ala}{Gln}{Asp}{Phe}{Val}{Gln}{Trp}{Leu}{Met}{Asn}{Thr}{Lys}{Arg}{Asn}{Arg}{Asn}{Asn}{Ile}{Ala}
Molecular Weight	4449.900
Application	DiabetesVeterinary Medicine

Wewer Albrechtsen, Nicolai J., et al. "Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes." American Journal of Physiology-Endocrinology and Metabolism 311.2 (2016): E302-E309.

Bagger, Jonatan Ising, et al. "Effect of oxyntomodulin, glucagon, GLP-1, and combined glucagon+ GLP-1 infusion on food intake, appetite, and resting energy expenditure." The Journal of Clinical Endocrinology & Metabolism 100.12 (2015): 4541-4552.

West, Graham M., et al. "Glucagon-like peptide-1 receptor ligand interactions: structural cross talk between ligands and the extracellular domain." PloS one 9.9 (2014).

Bak, Monika Judyta, et al. "Specificity and sensitivity of commercially available assays for glucagon and oxyntomodulin measurement in humans." Eur J Endocrinol 170.4 (2014): 529-538.

Albrechtsen, Nicolai J. Wewer, et al. "Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?." Diabetologia 57.9 (2014): 1919-1926.