mCRAMP (mouse)

Description:

CRAMP is a cathelin-related antimicrobial peptide expressed in both embryonic and adult mouse.

Sequence:

GLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPEQ
  • General
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  • Name mCRAMP (mouse)
    Category Antimicrobial and Related Peptides
    One Letter Code GLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPEQ
    Three Letter Code {Gly}{Leu}{Leu}{Arg}{Lys}{Gly}{Gly}{Glu}{Lys}{Ile}{Gly}{Glu}{Lys}{Leu}{Lys}{Lys}{Ile}{Gly}{Gln}{Lys}{Ile}{Lys}{Asn}{Phe}{Phe}{Gln}{Lys}{Leu}{Val}{Pro}{Gln}{Pro}{Glu}{Gln}
    Molecular Weight 3878.700
    Application Antimicrobial & Antiviral Peptides
    Iimura, Mitsutoshi, et al. "Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens." The journal of immunology 174.8 (2005): 4901-4907.
    López-García, Belén, et al. "Anti-fungal activity of cathelicidins and their potential role in Candida albicans skin infection." Journal of Investigative Dermatology 125.1 (2005): 108-115.
    Tripathi, Shweta, et al. "Antiviral activity of the human cathelicidin, LL-37, and derived peptides on seasonal and pandemic influenza A viruses." PLoS One 10.4 (2015).
    Bergman, Peter, et al. "Induction of the antimicrobial peptide CRAMP in the blood-brain barrier and meninges after meningococcal infection." Infection and immunity 74.12 (2006): 6982-6991.
    Saiman, Lisa, et al. "Cathelicidin peptides inhibit multiply antibiotic-resistant pathogens from patients with cystic fibrosis." Antimicrobial agents and chemotherapy 45.10 (2001): 2838-2844.
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