GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat)

Description:

Glucagon-Like Peptide 1 (GLP-1) is synthesized by posttranslational processing of proglucagon in the intestine and pancreas and plays an important role in metabolic homeostasis.

Sequence:

HDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG

General

References

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Name	GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat)
Category	Glucagons and Glucagon-Like Peptides (GLP-1 and GLP-2)
One Letter Code	HDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
Three Letter Code	{His}{Asp}{Glu}{Phe}{Glu}{Arg}{His}{Ala}{Glu}{Gly}{Thr}{Phe}{Thr}{Ser}{Asp}{Val}{Ser}{Ser}{Tyr}{Leu}{Glu}{Gly}{Gln}{Ala}{Ala}{Lys}{Glu}{Phe}{Ile}{Ala}{Trp}{Leu}{Val}{Lys}{Gly}{Arg}{Gly}
Molecular Weight	4169.540
Application	Diabetes

Gurlo, Tatyana, Peter C. Butler, and Alexandra E. Butler. "Evaluation of immunohistochemical staining for glucagon in human pancreatic tissue." Journal of histotechnology 39.1 (2016): 8-16.

Duan, Franklin F., Joy H. Liu, and John C. March. "Engineered commensal bacteria reprogram intestinal cells into glucose-responsive insulin-secreting cells for the treatment of diabetes." Diabetes 64.5 (2015): 1794-1803.

Edlund, Anna, et al. "CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells." BMC medicine 12.1 (2014): 87.

Bak, Monika Judyta, et al. "Specificity and sensitivity of commercially available assays for glucagon‐like peptide‐1 (GLP‐1): implications for GLP‐1 measurements in clinical studies." Diabetes, Obesity and Metabolism 16.11 (2014): 1155-1164.