GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)

Description:

GLP-1 (7-36) amide is considered as the most important incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells.

Sequence:

HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH₂

General

References

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Name	GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)
Category	Glucagons and Glucagon-Like Peptides (GLP-1 and GLP-2)
One Letter Code	HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH₂
Three Letter Code	{His}{Ala}{Glu}{Gly}{Thr}{Phe}{Thr}{Ser}{Asp}{Val}{Ser}{Ser}{Tyr}{Leu}{Glu}{Gly}{Gln}{Ala}{Ala}{Lys}{Glu}{Phe}{Ile}{Ala}{Trp}{Leu}{Val}{Lys}{Gly}{Arg}-NH₂
Molecular Weight	3297.680
Application	Diabetes

Naylor, Jacqueline, et al. "Automated Acoustic Dispensing for the Serial Dilution of Peptide Agonists in Potency Determination Assays." JoVE (Journal of Visualized Experiments) 117 (2016): e54542.

Dods, Rachel L., and Dan Donnelly. "The peptide agonist-binding site of the glucagon-like peptide-1 (GLP-1) receptor based on site-directed mutagenesis and knowledge-based modelling." Bioscience reports 36.1 (2016).

Gurlo, Tatyana, Peter C. Butler, and Alexandra E. Butler. "Evaluation of immunohistochemical staining for glucagon in human pancreatic tissue." Journal of histotechnology 39.1 (2016): 8-16.

Waser, Beatrice, et al. "Glucagon-like-peptide-1 receptor expression in normal and diseased human thyroid and pancreas." Modern pathology 28.3 (2015): 391-402.

Albrechtsen, Nicolai J. Wewer, et al. "Stability of glucagon-like peptide 1 and glucagon in human plasma." Endocrine connections 4.1 (2015): 50-57.