Glucagon - Like Peptide 1, GLP - 1 (7 - 36) - Lys(Biotin), amide (human)

Description:

GLP-1 (7-36) amide is considered as the most important incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells.

Sequence:

HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRK(Biotin)-NH2

General

References

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Name	Glucagon - Like Peptide 1, GLP - 1 (7 - 36) - Lys(Biotin), amide (human)
Category	Glucagons and Glucagon-Like Peptides (GLP-1 and GLP-2)
One Letter Code	HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRK(Biotin)-NH2
Three Letter Code	{His}{Ala}{Glu}{Gly}{Thr}{Phe}{Thr}{Ser}{Asp}{Val}{Ser}{Ser}{Tyr}{Leu}{Glu}{Gly}{Gln}{Ala}{Ala}{Lys}{Glu}{Phe}{Ile}{Ala}{Trp}{Leu}{Val}{Lys}{Gly}{Arg}{Lys(Biotin)}-NH2
Molecular Weight	3551.800
Application	Diabetes

Deacon, Carolyn F. "Circulation and degradation of GIP and GLP-1." Hormone and metabolic research 36.11/12 (2004): 761-765.

Williams, John A. "GLP-1." Pancreapedia: The Exocrine Pancreas Knowledge Base (2014).

Elahi, Dariush, et al. "GLP‐1 (9–36) amide, cleavage product of GLP‐1 (7–36) amide, is a glucoregulatory peptide." Obesity 16.7 (2008): 1501-1509.

Ban, Kiwon, et al. "Glucagon-like peptide (GLP)-1 (9-36) amide-mediated cytoprotection is blocked by exendin (9-39) yet does not require the known GLP-1 receptor." Endocrinology 151.4 (2010): 1520-1531.