[FAM - Trp

Description:

This GLP-1 (7-36) amide peptide is fluorescently labeled at Tryptophan residue 25 with Fluorescein. GLP-1 (7-36) amide is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells.

Sequence:

HAEGTFTSDVSSYLEGQAAKEFIA (Trp-S-FAM)-LVKGR-NH2
  • General
  • References
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  • Name [FAM - Trp
    Category Glucagons and Glucagon-Like Peptides (GLP-1 and GLP-2)
    One Letter Code HAEGTFTSDVSSYLEGQAAKEFIA (Trp-S-FAM)-LVKGR-NH2
    Three Letter Code {His}{Ala}{Glu}{Gly}{Thr}{Phe}{Thr}{Ser}{Asp}{Val}{Ser}{Ser}{Tyr}{Leu}{Glu}{Gly}{Gln}{Ala}{Ala}{Lys}{Glu}{Phe}{Ile}{Ala}{(Trp-S-FAM)}{Leu}{Val}{Lys}{Gly}{Arg}-NH2
    Molecular Weight 3717.500
    Application
    Deacon, Carolyn F. "Circulation and degradation of GIP and GLP-1." Hormone and metabolic research 36.11/12 (2004): 761-765.
    Williams, John A. "GLP-1." Pancreapedia: The Exocrine Pancreas Knowledge Base (2014).
    Elahi, Dariush, et al. "GLP‐1 (9–36) amide, cleavage product of GLP‐1 (7–36) amide, is a glucoregulatory peptide." Obesity 16.7 (2008): 1501-1509.
    Ban, Kiwon, et al. "Glucagon-like peptide (GLP)-1 (9-36) amide-mediated cytoprotection is blocked by exendin (9-39) yet does not require the known GLP-1 receptor." Endocrinology 151.4 (2010): 1520-1531.
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