GLP - 2 (1 - 34), Glucagon - Like Peptide - 2 (1 - 34) (human)

Description:

GLP2 is an intestinotrophic growth hormone that can rapidly improve intestinal epithelial barrier function.

Sequence:

HADGSFSDEMNTILDNLAARDFINWLIQTKITDR
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  • Name GLP - 2 (1 - 34), Glucagon - Like Peptide - 2 (1 - 34) (human)
    Category Glucagons and Glucagon-Like Peptides (GLP-1 and GLP-2)
    One Letter Code HADGSFSDEMNTILDNLAARDFINWLIQTKITDR
    Three Letter Code {His}{Ala}{Asp}{Gly}{Ser}{Phe}{Ser}{Asp}{Glu}{Met}{Asn}{Thr}{Ile}{Leu}{Asp}{Asn}{Leu}{Ala}{Ala}{Arg}{Asp}{Phe}{Ile}{Asn}{Trp}{Leu}{Ile}{Gln}{Thr}{Lys}{Ile}{Thr}{Asp}{Arg}
    Molecular Weight 3922.400
    Application Diabetes
    Yusta, Bernardo, et al. "Identification of glucagon-like peptide-2 (GLP-2)-activated signaling pathways in baby hamster kidney fibroblasts expressing the rat GLP-2 receptor." Journal of Biological Chemistry 274.43 (1999): 30459-30467.
    Drucker, Daniel J. "Biological actions and therapeutic potential of the glucagon-like peptides." Gastroenterology 122.2 (2002): 531-544.
    Koehler, J. A., B. Yusta, and D. J. Drucker. "The HeLa cell glucagon-like peptide-2 receptor is coupled to regulation of apoptosis and ERK1/2 activation through divergent signaling pathways." Molecular Endocrinology 19.2 (2005): 459-473.
    Vessey, Kirstan A., David A. Rushforth, and William K. Stell. "Glucagon-and secretin-related peptides differentially alter ocular growth and the development of form-deprivation myopia in chicks." Investigative ophthalmology & visual science 46.11 (2005): 3932-3942.
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