GLP-2 (1-33) (human)

Description:

GLP2 is an intestinotrophic growth hormone that can rapidly improve intestinal epithelial barrier function.

Sequence:

HADGSFSDEMNTILDNLAARDFINWLIQTKITD

General

References

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Name	GLP-2 (1-33) (human)
Category	Glucagons and Glucagon-Like Peptides (GLP-1 and GLP-2)
One Letter Code	HADGSFSDEMNTILDNLAARDFINWLIQTKITD
Three Letter Code	{His}{Ala}{Asp}{Gly}{Ser}{Phe}{Ser}{Asp}{Glu}{Met}{Asn}{Thr}{Ile}{Leu}{Asp}{Asn}{Leu}{Ala}{Ala}{Arg}{Asp}{Phe}{Ile}{Asn}{Trp}{Leu}{Ile}{Gln}{Thr}{Lys}{Ile}{Thr}{Asp}
Molecular Weight	3766.160
Application	Diabetes

Nakame, Kazuhiko, et al. "The protective and anti-inflammatory effects of glucagon-like peptide-2 in an experimental rat model of necrotizing enterocolitis." Peptides75 (2016): 1-7.

Waser, Beatrice, et al. "Incretin receptors in non-neoplastic and neoplastic thyroid C cells in rodents and humans: relevance for incretin-based diabetes therapy." Neuroendocrinology 94.4 (2011): 291-301.

Keane, Fiona M., et al. "Neuropeptide Y, B‐type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein‐α." The FEBS journal 278.8 (2011): 1316-1332.

Nuche‐Berenguer, Bernardo, et al. "Presence of a functional receptor for GLP‐1 in osteoblastic cells, independent of the cAMP‐linked GLP‐1 receptor." Journal of cellular physiology 225.2 (2010): 585-592.

Reubi, Jean-Claude, et al. "Glucagon-like peptide-1 (GLP-1) receptors are not overexpressed in pancreatic islets from patients with severe hyperinsulinaemic hypoglycaemia following gastric bypass." Diabetologia 53.12 (2010): 2641-2645.