GLP - 1(9 - 36), amide (human)

Description:

GLP-1 (9-36) is the result of the rapid degradation of GLP-1 (7-36)amide, by the enzyme dipeptidyl peptidase IV (DPP IV).

Sequence:

EGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2

General

References

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Name	GLP - 1(9 - 36), amide (human)
Category	Glucagons and Glucagon-Like Peptides (GLP-1 and GLP-2)
One Letter Code	EGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2
Three Letter Code	{Glu}{Gly}{Thr}{Phe}{Thr}{Ser}{Asp}{Val}{Ser}{Ser}{Tyr}{Leu}{Glu}{Gly}{Gln}{Ala}{Ala}{Lys}{Glu}{Phe}{Ile}{Ala}{Trp}{Leu}{Val}{Lys}{Gly}{Arg}-NH2
Molecular Weight	3089.500
Application	Diabetes

Bak, Monika Judyta, et al. "Specificity and sensitivity of commercially available assays for glucagon‐like peptide‐1 (GLP‐1): implications for GLP‐1 measurements in clinical studies." Diabetes, Obesity and Metabolism 16.11 (2014): 1155-1164.

Hou, Jack, et al. "Liraglutide, a long-acting GLP-1 mimetic, and its metabolite attenuate inflammation after intracerebral hemorrhage." Journal of Cerebral Blood Flow & Metabolism 32.12 (2012): 2201-2210.

Ma, Tao, et al. "Glucagon-like peptide-1 cleavage product GLP-1 (9-36) amide rescues synaptic plasticity and memory deficits in Alzheimer's disease model mice." Journal of Neuroscience 32.40 (2012): 13701-13708.

Nagashima, M., et al. "Native incretins prevent the development of atherosclerotic lesions in apolipoprotein E knockout mice." Diabetologia 54.10 (2011): 2649.

Hadjiyanni, I., et al. "Glucagon-like peptide-1 receptor signalling selectively regulates murine lymphocyte proliferation and maintenance of peripheral regulatory T cells." Diabetologia 53.4 (2010): 730-740.