[Des - octanoyl] - Ghrelin (human)

Description:

Des-octanoyl (or Des-acyl) Ghrelin is the unacylated precursor peptide to Ghrelin. Most circulating ghrelin is des-octanoyl ghrelin.

Sequence:

GSSFLSPEHQRVQQRKESKKPPAKLQPR

General

References

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Name	[Des - octanoyl] - Ghrelin (human)
Category	Ghrelin and Obestatin
One Letter Code	GSSFLSPEHQRVQQRKESKKPPAKLQPR
Three Letter Code	{Gly}{Ser}{Ser}{Phe}{Leu}{Ser}{Pro}{Glu}{His}{Gln}{Arg}{Val}{Gln}{Gln}{Arg}{Lys}{Glu}{Ser}{Lys}{Lys}{Pro}{Pro}{Ala}{Lys}{Leu}{Gln}{Pro}{Arg}
Molecular Weight	3244.700
Application	Obesity Research

Blatnik, Matthew, et al. "Prandial ghrelin attenuation provides evidence that des-acyl ghrelin may be an artifact of sample handling in human plasma." Bioanalysis 4.20 (2012): 2447-2455.

Gröschl, Michael, et al. "Evaluation of saliva collection devices for the analysis of steroids, peptides and therapeutic drugs." Journal of pharmaceutical and biomedical analysis 47.3 (2008): 478-486.

Kleinz, Matthias J., et al. "Functional and immunocytochemical evidence for a role of ghrelin and des-octanoyl ghrelin in the regulation of vascular tone in man." Cardiovascular research 69.1 (2006): 227-235.

Broglio, Fabio, et al. "Non-acylated ghrelin does not possess the pituitaric and pancreatic endocrine activity of acylated ghrelin in humans." Journal of endocrinological investigation 26.3 (2003): 192-196.