[Des - octanoyl] - Ghrelin (rat, mouse)

Description:

Des-octanoyl (or Des-acyl) Ghrelin is the unacylated precursor peptide to Ghrelin. Most circulating ghrelin is des-octanoyl ghrelin.

Sequence:

GSSFLSPEHQKAQQRKESKKPPAKLQPR

General

References

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Name	[Des - octanoyl] - Ghrelin (rat, mouse)
Category	Ghrelin and Obestatin
One Letter Code	GSSFLSPEHQKAQQRKESKKPPAKLQPR
Three Letter Code	{Gly}{Ser}{Ser}{Phe}{Leu}{Ser}{Pro}{Glu}{His}{Gln}{Lys}{Ala}{Gln}{Gln}{Arg}{Lys}{Glu}{Ser}{Lys}{Lys}{Pro}{Pro}{Ala}{Lys}{Leu}{Gln}{Pro}{Arg}
Molecular Weight	3188.700
Application	Obesity Research

Diaz-Ganete, Antonia, et al. "Ghrelin’s Effects on Proinflammatory Cytokine Mediated Apoptosis and Their Impact on β-Cell Functionality." International journal of endocrinology 2015 (2015).

Chen, Yung-Chu, et al. "Polymersomes conjugated with des-octanoyl ghrelin for the delivery of therapeutic and imaging agents into brain tissues." Biomaterials 35.6 (2014): 2051-2065.

Blatnik, Matthew, et al. "Prandial ghrelin attenuation provides evidence that des-acyl ghrelin may be an artifact of sample handling in human plasma." Bioanalysis 4.20 (2012): 2447-2455.

Toshinai, Koji, et al. "Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor." Endocrinology 147.5 (2006): 2306-2314.

Hosoda, Hiroshi, et al. "Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue." Biochemical and biophysical research communications 279.3 (2000): 909-913.