(Leu¹⁵)-Gastrin I (human)

Description:

This human Gastrin-1 analog is functionally the same as the native sequence,but this analog is more stable.

Sequence:

{pGLU}GPWLEEEEEAYGWLDF-NH₂
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  • Name (Leu¹⁵)-Gastrin I (human)
    Category Gastrin and Gastrin Releasing Peptide (GRP)
    One Letter Code {pGLU}GPWLEEEEEAYGWLDF-NH₂
    Three Letter Code {pGLU}{Gly}{Pro}{Trp}{Leu}{Glu}{Glu}{Glu}{Glu}{Glu}{Ala}{Tyr}{Gly}{Trp}{Leu}{Asp}{Phe}-NH₂
    Molecular Weight 2080.200
    Application Gastrointestinal Research
    Reubi, Jean Claude, Jean-Claude Schaer, and Beatrice Waser. "Cholecystokinin (CCK)-A and CCK-B/gastrin receptors in human tumors." Cancer research 57.7 (1997): 1377-1386.
    Zhao, Chun-Mei, et al. "ECL cells of the rat stomach: development of lipofuscin in response to sustained gastrin stimulation." Cell and tissue research 291.2 (1998): 315-323.
    Ryberg, B., et al. "Trophic effects of continuous infusion of [Leu15]-gastrin-17 in the rat." Gastroenterology 98.1 (1990): 33-38.
    Dubreuil, Phillibert, et al. "Novel activity of angiotensin-converting enzyme. Hydrolysis of cholecystokinin and gastrin analogues with release of the amidated C-terminal dipeptide." Biochemical Journal 262.1 (1989): 125-130.
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