Gastric Inhibitory Polypeptide (porcine)

Description:

N/A

Sequence:

YAEGTFISDYSIAMDKIRQQDFVNWLLAQKGKKSDWKHNITQ
  • General
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  • Name Gastric Inhibitory Polypeptide (porcine)
    Category Gastric Inhibitory Polypeptide (GIP) and Fragments
    One Letter Code YAEGTFISDYSIAMDKIRQQDFVNWLLAQKGKKSDWKHNITQ
    Three Letter Code {Tyr}{Ala}{Glu}{Gly}{Thr}{Phe}{Ile}{Ser}{Asp}{Tyr}{Ser}{Ile}{Ala}{Met}{Asp}{Lys}{Ile}{Arg}{Gln}{Gln}{Asp}{Phe}{Val}{Asn}{Trp}{Leu}{Leu}{Ala}{Gln}{Lys}{Gly}{Lys}{Lys}{Ser}{Asp}{Trp}{Lys}{His}{Asn}{Ile}{Thr}{Gln}
    Molecular Weight 4975.620
    Application Diabetes
    Fulurija, Alma, et al. "Vaccination against GIP for the treatment of obesity." PloS one 3.9 (2008).
    Singh, Satish K., et al. "Glucose‐dependent insulinotropic polypeptide (GIP) stimulates transepithelial glucose transport." Obesity 16.11 (2008): 2412-2416.
    Deacon, Carolyn F., et al. "GIP-(3–42) does not antagonize insulinotropic effects of GIP at physiological concentrations." American Journal of Physiology-Endocrinology and Metabolism 291.3 (2006): E468-E475.
    Kim, Su-Jin, et al. "Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic β-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression." Journal of Biological Chemistry 280.23 (2005): 22297-22307.
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