GIP (3 - 42) (human)

Description:

Gastric inhibitory polypeptide (GIP), an incretin, is an essential regulator of insulin secretion and glucose homeostasis.

Sequence:

EGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ
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  • Name GIP (3 - 42) (human)
    Category Gastric Inhibitory Polypeptide (GIP) and Fragments
    One Letter Code EGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ
    Three Letter Code {Glu}{Gly}{Thr}{Phe}{Ile}{Ser}{Asp}{Tyr}{Ser}{Ile}{Ala}{Met}{Asp}{Lys}{Ile}{His}{Gln}{Gln}{Asp}{Phe}{Val}{Asn}{Trp}{Leu}{Leu}{Ala}{Gln}{Lys}{Gly}{Lys}{Lys}{Asn}{Asp}{Trp}{Lys}{His}{Asn}{Ile}{Thr}{Gln}
    Molecular Weight 4759.400
    Application Diabetes
    Miyachi, Atsushi, et al. "Quantitative analytical method for determining the levels of gastric inhibitory polypeptides GIP1–42 and GIP3–42 in human plasma using LC–MS/MS/MS." Journal of proteome research 12.6 (2013): 2690-2699.
    Gault, V. A., et al. "Evidence that the major degradation product of glucose-dependent insulinotropic polypeptide, GIP (3-42), is a GIP receptor antagonist in vivo." Journal of Endocrinology 175.2 (2002): 525-534.
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