Galanin (1-13)-Neuropeptide Y (25-36) amide

Description:

The chimeric peptide M32 is a high affinity galanin receptor antagonist. M32 is also recognized by neuropeptide Y receptors

Sequence:

GWTLNSAGYLLGPRHYINLITRQRY-NH₂
  • General
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  • Name Galanin (1-13)-Neuropeptide Y (25-36) amide
    Category Galanin and Related Peptides
    One Letter Code GWTLNSAGYLLGPRHYINLITRQRY-NH₂
    Three Letter Code {Gly}{Trp}{Thr}{Leu}{Asn}{Ser}{Ala}{Gly}{Tyr}{Leu}{Leu}{Gly}{Pro}{Arg}{His}{Tyr}{Ile}{Asn}{Leu}{Ile}{Thr}{Arg}{Gln}{Arg}{Tyr}-NH₂
    Molecular Weight 2962.410
    Application
    Liu, Sumei, et al. "Actions of galanin on neurotransmission in the submucous plexus of guinea pig small intestine." European journal of pharmacology 471.1 (2003): 49-58.
    Kahl, Ulrika, et al. "Functional effects and ligand binding of chimeric galanin‐neuropeptide Y (NPY) peptides on NPY and galanin receptor types." British journal of pharmacology 111.4 (1994): 1129-1134.
    Arvidsson, Klas, et al. "Solution structure by 2D proton NMR of a chimeric peptide recognized by galanin and neuropeptide Y receptors." Biochemistry 32.30 (1993): 7787-7798.
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