Galanin-Like Peptide (porcine)

Description:

This member of the galanin family has been isolated from porcine hypothalamus. It is a 60 amino acid peptide that, unlike galanin, has a non-amidated C-terminus.

Sequence:

APVHRGRGGWTLNSAGYLLGPVLHPPSRAEGGGKGKTALGILDLWKAIDGLPYPQSQLAS

General

References

Comments (0)

Name	Galanin-Like Peptide (porcine)
Category	Galanin and Related Peptides
One Letter Code	APVHRGRGGWTLNSAGYLLGPVLHPPSRAEGGGKGKTALGILDLWKAIDGLPYPQSQLAS
Three Letter Code	{Ala}{Pro}{Val}{His}{Arg}{Gly}{Arg}{Gly}{Gly}{Trp}{Thr}{Leu}{Asn}{Ser}{Ala}{Gly}{Tyr}{Leu}{Leu}{Gly}{Pro}{Val}{Leu}{His}{Pro}{Pro}{Ser}{Arg}{Ala}{Glu}{Gly}{Gly}{Gly}{Lys}{Gly}{Lys}{Thr}{Ala}{Leu}{Gly}{Ile}{Leu}{Asp}{Leu}{Trp}{Lys}{Ala}{Ile}{Asp}{Gly}{Leu}{Pro}{Tyr}{Pro}{Gln}{Ser}{Gln}{Leu}{Ala}{Ser}
Molecular Weight	6204.110
Application

Kageyama, Haruaki, et al. "Anti-obesity effect of intranasal administration of galanin-like peptide (GALP) in obese mice." Scientific reports 6 (2016): 28200.

Seth, Asha, et al. "Effects of galanin-like peptide on food intake and the hypothalamo-pituitary-thyroid axis." Neuroendocrinology 77.2 (2003): 125-131.

Juréus, Anders, et al. "Galanin-like peptide (GALP) is a target for regulation by leptin in the hypothalamus of the rat." Endocrinology 141.7 (2000): 2703-2706.

Larm, Jari A., and Andrew L. Gundlach. "Galanin-like peptide (GALP) mRNA expression is restricted to arcuate nucleus of hypothalamus in adult male rat brain." Neuroendocrinology 72.2 (2000): 67-71.

Ohtaki, Tetsuya, et al. "Isolation and cDNA cloning of a novel galanin-like peptide (GALP) from porcine hypothalamus." Journal of Biological Chemistry 274.52 (1999): 37041-37045.