Magainin 1

Description:

Magainin I is thought to preferentially bind to anionic phospholipids abundant in bacterial membranes. With the formation of dynamic peptide-lipid supramolecular pore and cell permeabilization, magainins become positively charged and amphiphatic. Binding to artificial neutral membranes has also been demonstrated.

Sequence:

GIGKFLHSAGKFGKAFVGEIMKS

General

References

Comments (0)

Name	Magainin 1
Category	Antimicrobial and Related Peptides
One Letter Code	GIGKFLHSAGKFGKAFVGEIMKS
Three Letter Code	{Gly}{Ile}{Gly}{Lys}{Phe}{Leu}{His}{Ser}{Ala}{Gly}{Lys}{Phe}{Gly}{Lys}{Ala}{Phe}{Val}{Gly}{Glu}{Ile}{Met}{Lys}{Ser}
Molecular Weight	2409.900
Application	Antimicrobial & Antiviral Peptides

Matanic, Vanesa C. Albiol, and Viviana Castilla. "Antiviral activity of antimicrobial cationic peptides against Junin virus and herpes simplex virus." International journal of antimicrobial agents 23.4 (2004): 382-389.

Holub, Barbara S., et al. "Effects of galanin message-associated peptide and neuropeptide Y against various non-albicans Candida strains." International journal of antimicrobial agents 38.1 (2011): 76-80.

Psurek, Arndt, et al. "Nonaqueous versus aqueous capillary electrophoresis of α‐helical polypeptides: Effect of secondary structure on separation selectivity." Electrophoresis 27.9 (2006): 1768-1775.