Orphan GPCR SP9155 Agonist P518 (human)

Description:

P518 (human) is an RF-amide peptide ligand for SP9155, an orphan G-protein-coupled receptor with high homology to orexin, neuropeptide FF and CCK receptors.

Sequence:

TSGPLGNLAEELNGYSRKKGGFSFRF-NH₂

General

References

Comments (0)

Name	Orphan GPCR SP9155 Agonist P518 (human)
Category	FMRFamide and Related Neuropeptides
One Letter Code	TSGPLGNLAEELNGYSRKKGGFSFRF-NH₂
Three Letter Code	{Thr}{Ser}{Gly}{Pro}{Leu}{Gly}{Asn}{Leu}{Ala}{Glu}{Glu}{Leu}{Asn}{Gly}{Tyr}{Ser}{Arg}{Lys}{Lys}{Gly}{Gly}{Phe}{Ser}{Phe}{Arg}{Phe}-NH₂
Molecular Weight	2832.170
Application

Chartrel, Nicolas, et al. "Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity." Proceedings of the National Academy of Sciences 100.25 (2003): 15247-15252.

Jiang, Ying, et al. "Identification and characterization of a novel RF-amide peptide ligand for orphan G-protein-coupled receptor SP9155." Journal of Biological Chemistry 278.30 (2003): 27652-27657.