Neuropeptide AF (human)

Description:

The anti-opiate neuropeptide NPSF play an important role in pain modulation and opioid tolerance.

Sequence:

AGEGLNSQFWSLAAPQRF-NH₂
  • General
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  • Name Neuropeptide AF (human)
    Category FMRFamide and Related Neuropeptides
    One Letter Code AGEGLNSQFWSLAAPQRF-NH₂
    Three Letter Code {Ala}{Gly}{Glu}{Gly}{Leu}{Asn}{Ser}{Gln}{Phe}{Trp}{Ser}{Leu}{Ala}{Ala}{Pro}{Gln}{Arg}{Phe}-NH₂
    Molecular Weight 1978.200
    Application Opioid Research
    Palotai, Miklós, et al. "The action of neuropeptide AF on passive avoidance learning. Involvement of neurotransmitters." Neurobiology of Learning and Memory127 (2016): 34-41.
    Jászberényi, Miklós, et al. "Endocrine, behavioral and autonomic effects of neuropeptide AF." Hormones and behavior 56.1 (2009): 24-34.
    Lefrère, Isabelle, et al. "Neuropeptide AF and FF Modulation of Adipocyte Metabolism PRIMARY INSIGHTS FROM FUNCTIONAL GENOMICS AND EFFECTS ON β-ADRENERGIC RESPONSIVENESS." Journal of Biological Chemistry 277.42 (2002): 39169-39178.
    Elshourbagy, Nabil A., et al. "Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor." Journal of Biological Chemistry 275.34 (2000): 25965-25971.
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