Melittin (honey bee)

Description:

Melittin, a 26-residue bee venom peptide, is known to induce murine antibodies specific for its hydrophilic C-terminus of residues 20 to 26 and T-cell responses specific for its hydrophobic mid-region .This peptide is an anti-inflammatory agent, it inhibits the lyme disease spirochete.

Sequence:

GIGAVLKVLTTGLPALISWIKRKRQQ-NH2

General

References

Comments (0)

Name	Melittin (honey bee)
Category	Antimicrobial and Related Peptides
One Letter Code	GIGAVLKVLTTGLPALISWIKRKRQQ-NH2
Three Letter Code	{Gly}{Ile}{Gly}{Ala}{Val}{Leu}{Lys}{Val}{Leu}{Thr}{Thr}{Gly}{Leu}{Pro}{Ala}{Leu}{Ile}{Ser}{Trp}{Ile}{Lys}{Arg}{Lys}{Arg}{Gln}{Gln}-NH2
Molecular Weight	2846.500
Application

Smith, Ross, et al. "Structure and orientation of the pore-forming peptide melittin, in lipid bilayers." Journal of molecular biology 241.3 (1994): 456-466.

King, Te Piao, et al. "Structure-immunogenicity relationship of melittin, its transposed analogues, and D-melittin." The Journal of Immunology 153.3 (1994): 1124-1131.