H-Arg-Gly-Asp-Ser-OH

Description:

RGDS, a tetrapeptide which supports fibroblast attachment and inhibits fibronectin binding to platelets. RGDS is a target sequence for syphilis spirochete cytadherence.

Sequence:

RGDS
  • General
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  • Name H-Arg-Gly-Asp-Ser-OH
    Category Fibronectin Fragments, RGD Peptides
    One Letter Code RGDS
    Three Letter Code {Arg}{Gly}{Asp}{Ser}
    Molecular Weight 433.420
    Application Adhesion Molecules & Extracellular Matrix ProteinsCell CultureRegenerative Medicine
    Elomaa, Laura, et al. "Three-dimensional fabrication of cell-laden biodegradable poly (ethylene glycol-co-depsipeptide) hydrogels by visible light stereolithography." Journal of Materials Chemistry B 3.42 (2015): 8348-8358.
    Inoue, Takayuki, et al. "In Vivo Analysis of Arg‐Gly‐Asp Sequence/Integrin α5β1‐Mediated Signal Involvement in Embryonic Enchondral Ossification by Exo Utero Development System." Journal of Bone and Mineral Research 29.7 (2014): 1554-1563.
    Tavoosi, Narjes, et al. "Factor VII and protein C are phosphatidic acid-binding proteins." Biochemistry 52.33 (2013): 5545-5552.
    Gerrits, Anja J., et al. "Induction of insulin resistance by the adipokines resistin, leptin, plasminogen activator inhibitor-1 and retinol binding protein 4 in human megakaryocytes." Haematologica 97.8 (2012): 1149-1157.
    Chen, Shali, et al. "Regulation of vascular endothelial growth factor expression by extra domain B segment of fibronectin in endothelial cells." Investigative ophthalmology & visual science 53.13 (2012): 8333-8343.
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