H-Arg-Phe-Asp-Ser-OH

Description:

RFDS, an analog of the RGD peptide RGDS, inhibits cell adhesion.The motif RFDS was found highly conserved in MHC class I (α1 domain) and class II antigens (β1 domain).

Sequence:

RFDS

General

References

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Name	H-Arg-Phe-Asp-Ser-OH
Category	Fibronectin Fragments, RGD Peptides
One Letter Code	RFDS
Three Letter Code	{Arg}{Phe}{Asp}{Ser}
Molecular Weight	523.550
Application	Adhesion Molecules & Extracellular Matrix ProteinsRegenerative Medicine

Ruf, Andreas, et al. "Contact-induced neutrophil activation by platelets in human cell suspensions and whole blood." (1992): 1238-1246.

Lawrence, Jeffry B., et al. "Arginine-glycine-aspartic acid-and fibrinogen gamma-chain carboxyterminal peptides inhibit platelet adherence to arterial subendothelium at high wall shear rates. An effect dissociable from interference with adhesive protein binding." The Journal of clinical investigation 86.5 (1990): 1715-1722.

Auffray, Charles, and Jiri Novotny. "Speculations on sequence homologies between the fibronectin cell-attachment site, major histocompatibility antigens, and a putative AIDS virus polypeptide." Human immunology 15.4 (1986): 381-390.