GRGDSPK

Description:

A linear integrin binding peptide. It inhibits endothelial cell adhesion to fibroblast growth factor-2 and to fibronectin.

Sequence:

GRGDSPK

General

References

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Name	GRGDSPK
Category	Fibronectin Fragments, RGD Peptides
One Letter Code	GRGDSPK
Three Letter Code	{Gly}{Arg}{Gly}{Asp}{Ser}{Pro}{Lys}
Molecular Weight	715.800
Application	Adhesion Molecules & Extracellular Matrix ProteinsRegenerative Medicine

Kumar, C. Chandra, et al. "Inhibition of angiogenesis and tumor growth by SCH221153, a dual αvβ3 and αvβ5 integrin receptor antagonist." Cancer Research 61.5 (2001): 2232-2238.

Rusnati, Marco, et al. "αvβ3 integrin mediates the cell-adhesive capacity and biological activity of basic fibroblast growth factor (FGF-2) in cultured endothelial cells." Molecular Biology of the Cell 8.12 (1997): 2449-2461.