GRGDS, amide

Description:

This peptide inhibits the adhesion of human ovarian carcinoma OVCAR-3 cells to fibronectin, but not to laminin.

Sequence:

GRGDS-NH2
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  • Name GRGDS, amide
    Category Fibronectin Fragments, RGD Peptides
    One Letter Code GRGDS-NH2
    Three Letter Code {Gly}{Arg}{Gly}{Asp}{Ser}-NH2
    Molecular Weight 489.500
    Application Adhesion Molecules & Extracellular Matrix ProteinsCancer ResearchRegenerative Medicine
    Kanemoto, T., et al. "Effects of synthetic peptides and protease inhibitors on the interaction of a human ovarian cancer cell line (NIH: OVCAR-3) with a reconstituted basement membrane (Matrigel)." Invasion & metastasis 11.2 (1991): 84-92.
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