H-Gly-Arg-Gly-Asp-Asn-Pro-OH

Description:

Potent inhibitor of cell attachment to fibronectin.

Sequence:

GRGDNP
  • General
  • References
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  • Name H-Gly-Arg-Gly-Asp-Asn-Pro-OH
    Category Fibronectin Fragments, RGD Peptides
    One Letter Code GRGDNP
    Three Letter Code {Gly}{Arg}{Gly}{Asp}{Asn}{Pro}
    Molecular Weight 614.620
    Application Adhesion Molecules & Extracellular Matrix ProteinsRegenerative Medicine
    Toyoshima, Fumiko, and Eisuke Nishida. "Integrin‐mediated adhesion orients the spindle parallel to the substratum in an EB1‐and myosin X‐dependent manner." The EMBO journal26.6 (2007): 1487-1498.
    Koyanagi, Masamichi, et al. "Differentiation of circulating endothelial progenitor cells to a cardiomyogenic phenotype depends on E‐cadherin." FEBS letters 579.27 (2005): 6060-6066.
    Peake, M. A., et al. "Selected contribution: regulatory pathways involved in mechanical induction of c-fos gene expression in bone cells." Journal of Applied Physiology 89.6 (2000): 2498-2507.
    Mogford, Jon E., George E. Davis, and Gerald A. Meininger. "RGDN peptide interaction with endothelial alpha5beta1 integrin causes sustained endothelin-dependent vasoconstriction of rat skeletal muscle arterioles." The Journal of clinical investigation 100.6 (1997): 1647-1653.
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