Fibrinolysis Inhibiting Factor

Description:

This peptide mimics the N terminus of the alpha-chain of fibrin.

Sequence:

GPRP

General

References

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Name	Fibrinolysis Inhibiting Factor
Category	Fibronectin Fragments, RGD Peptides
One Letter Code	GPRP
Three Letter Code	{Gly}{Pro}{Arg}{Pro}
Molecular Weight	425.500
Application	Cardiovascular Related Peptides

Pratt, K. P., et al. "The primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal γ chain fragment complexed with the peptide Gly-Pro-Arg-Pro." Proceedings of the National Academy of Sciences 94.14 (1997): 7176-7181.

Lorand, Laszlo, Kumarapuram N. Parameswaran, and SN Prasanna Murthy. "A double-headed Gly-Pro-Arg-Pro ligand mimics the functions of the E domain of fibrin for promoting the end-to-end crosslinking of γ chains by factor XIIIa." Proceedings of the National Academy of Sciences 95.2 (1998): 537-541.